#16: Adding sex determination from Hare and visualizing missingness
In today’s meeting I will be presenting a notebook stored as a PDF. This noteboks contains methods for loading Hare data, pulling out sex specification, and incorporating this information into our matrix table.
This new information can now be used to set sex specific paramaters for filtering variants. In addition to adding sex specification, the notebook shown today includes methods for filtering the X and Y chromosomes based on gender and a plot to visualize variant missingness per sample in chromosomes.
In a seperate notbook, I am currently comparing our previous filtering method to this new method that incorporates sex specific filtering. Preliminary observations suggest there is no change. I am currently taking steps to validate that both the method is working correctly and that adding a sex filter has no affect.
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